Validation in Genomics: CpG Island Methylation Revisited

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Validation in genomics: CpG island methylation revisited.

In a recent article in PLoS Genetics, Bock et al., (2006) undertake an extensive computational epigenetics analysis of the ability of DNA sequence-derived features, capturing attributes such as tetramer frequencies, repeats and predicted structure, to predict the methylation status of CpG islands. Their suite of analyses appears highly rigorous with regard to accompanying validation procedures,...

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ژورنال

عنوان ژورنال: Statistical Applications in Genetics and Molecular Biology

سال: 2006

ISSN: 1544-6115

DOI: 10.2202/1544-6115.1256